[HTML][HTML] Inflammation is associated with worse outcome in the whole cohort but with better outcome in triple-negative subtype of breast cancer patients
Journal of Immunology Research, 2020•ncbi.nlm.nih.gov
Inflammation has been linked with cancer, but whether it is part of the problem or part of the
solution remains to be a matter of debate in breast cancer. Our group and others have
demonstrated that inflammation aggravates cancer progression; however, some claim that
inflammation may support immune cell infiltration and suppress cancer. We defined the
gene set variation analysis of the Molecular Signatures Database Hallmark inflammatory
response gene set as the inflammatory pathway score and analyzed 3632 tumors in total …
solution remains to be a matter of debate in breast cancer. Our group and others have
demonstrated that inflammation aggravates cancer progression; however, some claim that
inflammation may support immune cell infiltration and suppress cancer. We defined the
gene set variation analysis of the Molecular Signatures Database Hallmark inflammatory
response gene set as the inflammatory pathway score and analyzed 3632 tumors in total …
Abstract
Inflammation has been linked with cancer, but whether it is part of the problem or part of the solution remains to be a matter of debate in breast cancer. Our group and others have demonstrated that inflammation aggravates cancer progression; however, some claim that inflammation may support immune cell infiltration and suppress cancer. We defined the gene set variation analysis of the Molecular Signatures Database Hallmark inflammatory response gene set as the inflammatory pathway score and analyzed 3632 tumors in total from 4 breast cancer cohorts (METABRIC, TCGA,
ncbi.nlm.nih.gov
